Dr. rer. nat. Michel V. Hadjihannas

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1. Bernkopf DB, M. Brückner, MV. Hadjihannas, J. Behrens (2019) Nat Commun. Sep 18;10(1):4251.
An aggregon in conductin/axin2 regulates Wnt/ß-catenin signaling and holds potential for cancer therapy.

2. Vasileiou G, Ekici AB, Uebe S, Zweier C, Hoyer J, Engels H, Behrens J, Reis A, Hadjihannas MV. (2015) Am J Hum Genet. Sep 3;97(3):445-56.
Chromatin-Remodeling-Factor ARID1B Represses Wnt/ß-Catenin Signaling.

3. Bernkopf DB, MV. Hadjihannas, Behrens J. (2015) J Cell Sci. Jan 1;128(1):33-9.
Negative-feedback regulation of the Wnt pathway by conductin/axin2 involves insensitivity to upstream signalling.

4. Brauburger, K., S. Akyildiz, J. Ruppert, M. Graeb, D. Bernkopf, MV. Hadjihannas and J. Behrens. (2014) FEBS J. Feb;281(3):787-801.
Amer3, a member of the Amer family of APC binding proteins is a positive regulator of Wnt/b-catenin signalling.

5. Pfister, A.S., MV. Hadjihannas, W. Röhrig, A. Schambony, J. Behrens. (2012) J Biol Chem 287(42): p. 35333-40.
Amer2 protein interacts with EB1 protein and adenomatous polyposis coli (APC) and controls microtubule stability and cell migration.

6. Hadjihannas, M.V., D.B. Bernkopf, M. Bruckner, and J. Behrens (2012) EMBO Rep. 13:347.
Cell cycle control of Wnt/b-catenin signalling by conductin/axin2 through CDC20.

7. Tanneberger, K, AS. Pfister, K. Brauburger, J. Schneikert, MV. Hadjihannas, V. Kriz, G. Schulte, V. Bryja, J. Behrens (2011) EMBO J 30: p. 1433-1443.
Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P(2) to LRP6 phosphorylation.

8. Hadjihannas, M.V., M. Bruckner, and J. Behrens (2010) EMBO Rep. 11: p. 317-24. (F1000)
Conductin/axin2 and Wnt signalling regulates centrosome cohesion.

9. Dehner, M., MV. Hadjihannas, J. Weiske, O.Huber, J. Behrens. (2008) J Biol Chem 283(28): p. 19201-10.
Wnt signaling inhibits Forkhead box O3a-induced transcription and apoptosis through up-regulation of serum. And glucocorticoid-inducible kinase 1.

10. Hadjihannas, M.V. and J. Behrens (2006) Cell Cycle. 5: p. 2077-81.
CIN By WNT: growth pathways, mitotic control and chromosomal instability in cancer.

11. Hadjihannas, M.V., M. Bruckner, B. Jerchow, W. Birchmeier, W. Dietmaier, and J. Behrens. (2006) Proc Natl Acad Sci U S A. 103: p. 10747-52.
Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer.